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Propylene glycol

Propylene glycol is an organic compound with a molecular formula of C3H8O2 and a molecular weight of 76.09. There are two configurations, R and S. The two configurations are usually not harmful to water. Do not discharge the material into the surrounding environment without government permission. Keep it in a dark, ventilated and dry place, sealed. It is widely used in the synthesis of chiral drugs.

Propylene oxide hydration

Propylene oxide reacts with water at 200°C and 1-20MPa reaction conditions to produce 1,2-propanediol. The waste discharge is small, the equipment is low in corrosiveness, the product purity is high, and the stability is strong, but the reaction is relatively harsh and the equipment investment is relatively large.

At present, domestic and foreign companies adopting propylene oxide hydration process mainly include Lyondell, Dow, Basf, and CNOOC and Shell.


Under normal pressure and 65°C, propylene carbonate (PC) and methanol undergo transesterification reaction with sodium methoxide as a catalyst to produce 1,2 propanediol. The method has low production cost, complicated refining process of a single product, relatively poor quality, serious environmental pollution, and low yield.

At present, most domestic manufacturers use the transesterification method to produce propylene glycol.

Dichloropropane hydrolysis

The dichloropropane method is divided into direct hydrolysis and first esterification and then hydrolysis. Direct hydrolysis is the hydrolysis of dichloropropane in a weak base solution; first esterification and then hydrolysis is a process in which dichloropropane reacts with acid salts to form esters, and esters are hydrolyzed into alcohols.

This method has high environmental pollution and high cost.


It is advisable to choose galvanized iron drums, aluminum or stainless steel containers, store them in a dike, air circulation, and not exposed to sunlight, open flames and other heat sources. Keep the container tightly closed and dry.


Pharmaceutical grade, food grade, industrial grade

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